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After the Battle of Ridaniya in 1517, the city was conquered by the Ottoman Turks and remained under Ottoman rule until 1798.Alexandria lost much of its former importance to the Egyptian port city of Rosetta during the 9th to 18th centuries, and only regained its former prominence with the construction of the Mahmoudiyah Canal in 1807.The city was later plundered and lost its significance.In the early Christian Church, the city was the center of the Patriarchate of Alexandria, which was one of the major centers of early Christianity in the Eastern Roman Empire.A few months after the foundation, Alexander left Egypt and never returned to his city.
Hellenistic Alexandria was best known for the Lighthouse of Alexandria (Pharos), one of the Seven Wonders of the Ancient World; its Great Library (the largest in the ancient world; now replaced by a modern one); and the Necropolis, one of the Seven Wonders of the Middle Ages.
However, more recent radiocarbon dating of seashell fragments and lead contamination predate this claim by two millennia Alexandria was the intellectual and cultural center of the ancient world for some time.
The city and its museum attracted many of the greatest scholars, including Greeks, Jews and Syrians.
From the late 18th century, Alexandria became a major center of the international shipping industry and one of the most important trading centers in the world, both because it profited from the easy overland connection between the Mediterranean Sea and the Red Sea, and the lucrative trade in Egyptian cotton. Alexander's chief architect for the project was Dinocrates.
Alexandria was intended to supersede Naucratis as a Hellenistic center in Egypt, and to be the link between Greece and the rich Nile valley.
The Septuagint, a Greek version of the Tanakh, was produced there.